A NOVEL PEPTIDE ANTIBIOTIC PRODUCED BY STREPTOMYCES ROSEOFLAVUS STRAIN INA-AC-5812 WITH DIRECTED ACTIVITY AGAINST GRAM-POSITIVE BACTERIA

A Novel Peptide Antibiotic Produced by Streptomyces roseoflavus Strain INA-Ac-5812 With Directed Activity Against Gram-Positive Bacteria

In this work, we report the isolation and detailed functional characterization for the new non-ribosomally synthesized antibiotic 5812-A/C, which was derived from metabolites of Streptomyces roseoflavus INA-Ac-5812.According to its chemical structure, the studied 5812-A/C preliminary is composed of a cyclic peptide part covalently bounded with an a

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Plague and the Human Flea, Tanzania

Domestic fleas were collected in 12 villages in the western Usambara Mountains Leather Keychain in Tanzania.Of these, 7 are considered villages with high plague frequency, where human plague was recorded during at least 6 of the 17 plague seasons between 1986 and 2004.In the remaining 5 villages with low plague frequency, plague was either rare or

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